How to use Anadrol (Oxymetholone) to increase muscle mass

Jason Williams

The androgen-anabolic steroid Oxymetholone, known in the world of sports as Anadrol, is currently enjoying unprecedented popularity. The original goal of scientists in the invention of this steroid was the treatment of various pathologies.

 However, among bodybuilders, this substance began to be in demand precisely after the advertisement came out, where the titled bodybuilder from the USA Daniel Duchaine took part. Many know him as the “Steroid Guru.” It was Daniel who praised Anapol (another name for Oxymetholone) as an affordable alternative to Danabol. And, as it turned out, he did it for good reason. Indeed, at the moment, Anadrol is recognized as one of the strongest pharmacological agents that has been used by athletes of various varieties of sports for half a century.

General information about the great and powerful Oxymetholone

 This drug is a synthetic steroid, the anabolic effect of which is pronounced. Initially, this substance was developed for the treatment of osteoporosis, anemia and as a maintenance of muscular strength in patients who were poorly fed or were weakened due to any past pathologies.

 The key effect of anabolic is aimed at increasing the production of red blood cells by stimulating the production of erythropoietin (a natural hormone). Due to this, oxygen begins to flow better to cells in the body.

 Since the 2000s, Anadrol has been very actively used in the sports field, but most of all in bodybuilding. Used it only at the pre-competitive stage. The fact was that for a long time its anabolic effect was confined to the ability to retain fluid in the body (it was assumed that this factor provided a strong weight gain). However, nowadays, the use of Oxymetholone is not limited to taking exclusively in the pre-competition period.

 And here it is worth saying that this drug is recognized as a powerful synthetic anabolic. As a rule, athletes who want to quickly build muscle are taking this steroid for themselves.

 Anapolon enters the pharmacological market in two formats:

  • Injectable.
  • And tableted.

 In addition, this anabolic is characterized by the highest anabolic activity (protein synthesis increases significantly). Just imagine, as much as 320% of testosterone (while testosterone itself has only 100%). Simply put, this steroid accelerates protein synthesis to such an extent that the athlete begins to gain weight right before his eyes. And most importantly, with all this, the parameter of androgenic activity (we are talking about the manifestation of male traits in the fair sex, as well as the suppression of these traits in the male community) is only 30% of testosterone. Which is negligible.


 If we talk about the use of this anabolic in the field of medicine, then it enters into battle with such ailments as:

  • Dystrophy.
  • Cancer (increases vitality and helps to gain weight).
  • Radiation sickness.
  • HIV.

 Also, this drug has proven to be an excellent tool for the treatment of injuries in sports.

 In general, Anadrol has a unique ability – it contributes to weight gain in the shortest amount of time. And more precisely – about 15 kg in just one course.

Anapolon historical excursion – from treatment of osteoporosis to application in the sports field

 But the historical excursion of Anapolon is extremely interesting. For the first time this drug was heard in the 60s. It was during this period of time that he appeared on the market. Syntex Pharmaceuticals was developing at the time. The drug was produced specifically for the treatment of such an ailment as osteoporosis, activation of muscle growth, increased appetite, as well as for the therapeutic treatment of anemia, provoked by the inadequate production of red blood cells. Due to this effect, this drug is prescribed for patients with problems in the field of weight gain, provoked by:

  • Exhausting pathologies.
  • Burns and other injuries.
  • Surgical interventions.

 But, despite the fact that Oxymetholone received approval from the FDA for use in humans, a little later they conducted research work, which showed that there are also the most suitable steroids to combat anemia and osteoporosis. But, even despite the list of “side effects”, the historical excursion did not end there, and Anadrol showed itself perfectly both in the medical field and in professional sports. In addition, he perfectly established himself as a medicine aimed at maintaining the health of patients whose immunity is weakened against the background of HIV infection.

 However, by the beginning of the 90s, the production of this drug was stopped. Everything as usual – simply found a replacement for Anadrol. However, the generic did not manage to take root in the pharmacology market. So now Oxymetholone is in huge demand.

 This steroid is rightfully recognized as one of the strongest. And as for its effectiveness in relation to a set of muscle strength, it at times prevails over the effectiveness of testosterone.

Anadrol’s work – is it true that this is a “quick bomb”

 The work of Anadrol is that he:

  • Helps accelerate the emergence of new cells.
  • Increases metabolism.
  • Accelerates the synthesis of hemoglobin.
  • Stimulates bleeding.

The first thing this substance does is to create favorable conditions for the reproduction of collagen. And collagen, in turn, increases the elasticity of the musculoskeletal tissue, which allows it to withstand significant loads.

 In addition, the work of Oxymetholone  is not only an increase in body weight. It also contributes to the process of activating other systems that are directly involved in increasing water and fat levels. And this is another plus in effective weight.

 Is it true that this is a “quick bomb”? The answer is clear – yes, true. The speed of this substance is so high that you can already feel the full power of the anabolic in the first days of the cycle. Well, Anadrol will reveal all the pharmacological internal reserves after three to five weeks. It turns out that the courses with its application are quite short. However, he does not lose his effectiveness.

 As mentioned above, it is believed that this drug retains fluid. But with these features, it is also characterized by excellent fat-burning actions. The greatest effect is noticeable in the abdomen. And this is precisely the area that is difficult to “eliminate” fatty deposits.

How to use oxymetholone to bypass side effects

 Of course, many are interested in the very logical question: “How to use Oxymetholone?”. The course with this substance is prescribed for athletes in the age category 18+, if there are no contraindications. Well, in general, doctors recommend taking this anabolic from the age of 21.

 It is used, as a rule, at the stage of gaining muscle mass, in the offseason. Its use is advisable at the very beginning of a long course of steroids. This is necessary in order to dramatically “load” the work of all the tools used. Before embarking on a course, you should definitely be fully examined in a medical institution and consult with a specialist.

 As for the dosage and duration of the course, then everything is calculated individually. And, of course, the goal, the pharmacological experience and the characteristics of the organism take place. The recommended duration of use of Anadrol is from four to six weeks. But it is best not to exceed this duration, since the substance is hepatoxic enough and the effectiveness of this will not increase. On the contrary, the appearance of a “side effect” is possible. So neglect the recommended duration of the course is not worth it.

 As for the time of admission, in the case of Oxymetholone, from whether you take it after a meal or before, the result will not be affected at all. After course therapy, PCT (post-cycle therapy) is required.

 In certain circumstances, professional bodybuilders are allowed a single dose of high doses of Anapolon immediately before the start. This approach makes it possible to obtain a powerful accumulation of glycogen. From here – voluminous and full of muscles.

 In addition, athletes with intolerance to steroids with an androgenic high index can also use this tool. As a rule, this applies to those athletes who, due to heredity, are likely to have prostate hypertrophy, as well as baldness.

 If it is about sports, then experts recommend the use of this steroid exclusively during a difficult training process. This can be an isolated course, or combined with other substances. And the thing is that Anadrol enhances metabolic processes, but it has a weak effect on the glands, which are responsible for the production of androgens (these are sex hormones), thereby provoking their deficiency. So, in order to increase the efficiency, hormone replenishment from the outside is allowed through the combined use of Anapolon with other substances (an excellent companion in this matter is Testosterone Enanthate).

How to use oxymetholone

 But as for drying, due to the significant water retention, Oxymetholone is prescribed in rare cases. But if, nevertheless, this drug is used in drying, then hormones (Prolactin and Estradiol) should be controlled.

 To achieve maximum performance, do not forget not only to follow the instructions for use, but also about a special diet for building muscle strength. Not superfluous – the acquisition and use of integrated sports nutrition.

 But specialists during the course advise to train hard, fill with protein and calcium nutrition, as well as healthy and sound sleep. As for alcohol and psychotropic substances, this is a taboo.

 Also, do not forget that the course of Anapolon will allow you to achieve the greatest effectiveness not in the case of the “ladder” or “pyramid” course, namely when using the same standard dosage, from the beginning to the very end of the cycle.

What dosages of Anadrol are recommended for men, in particular for the most fierce “chemists”

 And here is the most important question: “What dosages of Anadrol are recommended?” In most cases, the initial dosage is 50 mg per day. It is suitable for lovers and male beginners. However, for the most fierce “chemists”, 150 mg per day may be needed. This, of course, is only for the pros.

 Here it is worth saying that there are also those daredevils who consume 300 mg per day. This is not worth doing. After all, only a few units when using such a dosage indicate the greatest efficiency. And then these changes occur against the background of combination with other anabolic steroids. Therefore, the best thing is to wait a couple of days before increasing the dosage. This is the only way to make sure that you are actually lacking the current dosage.

Oxymetholone Cycles – Are Mixes Possible with Other Steroids

To the question: “Are” mixes “possible with other steroids” you can safely and firmly answer “yes.” However, there is one “but.” Oxymetholone cycles in tandem with 17-alpha-alkyl steroids are not recommended by specialists. Taking into account a very fast anabolic effect, Anadrol is great for a “quick start” – the effect is felt almost instantly.

Read also: Hand Workouts: 5 Ways to Blow Your Biceps

 So, to gain muscle mass, the recommended combination of Anapolon with:

  • Boldenone.
  • Trenbolone.
  • Primobolan.
  • Deca-Durabolin.
  • Sustanon-250.
  • Methenolone.

 To increase strength indicators, combinations with a suspension of stanozolol and testosterone esters are suitable.

 But the following are recognized as the most successful combinations:

  1. For muscle gain – Oxymetholone (40 tablets) + Boldenone (10 ml) + Provimed (20 tablets) + Clomid (20 tablets). This is a great variation for those who need to quickly build muscle strength, as well as increase strength indicators. So, if your goal is a radical change in physical form, then this combination is just what you need. With each week, the anabolic effect will only increase.
  2. To increase strength indicators – Anadrol (40 tablets) + Clomid (20 tablets) + Winstrol (20 ml). For beginners, this cycle will not be the best variation. But for pros or amateurs, behind whom a wealth of experience using steroids is the same. The result will turn out to be of high quality.

 As for the duration of the course, in both cases it is no more than ten weeks.

Anadrol dosage for women – is this drug dangerous for female athletes?

Despite the fact that the vast majority believes that Anapolon is almost the most terrible drug for beautiful women due to the symptoms of virilization, the practice suggests the opposite. Based on medical studies, during which the attractive young athletes took Anadrol at a dosage of 50 mg per day for a long period of time, only a minimal probability of virilization symptoms was revealed.

 Of course, the daily dosage of 50 mg for bodybuilding pros is not high. However, for a significant mass of athletes, this dosage will be enough to surpass the result. Even the dosage of Anapolon for women in 25 mg will be accompanied by a good result. And with all this, the risk of adverse reactions will be minimized.

 The duration of the course for experienced athletes should not exceed more than eight weeks. If we are talking about female novices or amateurs, then the duration of the cycle should be no more than four weeks.

The effect of the use of Anadrol – are there any “pitfalls”

Some when using anabolic steroids are afraid, so to speak, of “pitfalls”. What if the effect of Anadrol is not expected? You can not worry, the positive features of the steroid will be immediately noticeable:

  • Dense, stiff and solid muscular strength builds up. On average, about 10 kg, but the maximum value reaches 15 kg (we are talking only about one course of solo). And here it’s worth saying that this steroid is known precisely as a highly effective anabolic “tool” regarding rapid weight gain. The parameter of its set is incomparable with any other similar anabolic. Due to this, Oxymetholone is a favorite of a significant number of athletes at the off-season stage. In some cases, before the competition itself.
  • Significantly increase physical strength. And this in turn will affect the athlete’s performance and, of course, his self-confidence. This drug is able to accumulate glycogen and fluid in the body. Thus, in the shortest possible time, strength indicators increase. And this is the best variation for representatives of power varieties of sports.
  • The degree of endurance will increase, which will allow to carry out planned training processes more intensively. And endurance increases due to an increase in the number of red blood cells.
  • In addition, joint mobility will increase, as well as prevention of the occurrence of pain in the joints themselves, and existing pains will self-destruct.
  • The amount of fat in the abdomen will decrease.

 In general, the effect is definitely not long in coming.

Adverse Reactions of Oxymetholone – What You Can Face in Practice

This substance was often simply shrouded in scary stories of insane undesirable manifestations. However, a significant part of the adverse reactions of Oxymetholone manifests itself in the event that the level of estradiol is overestimated. And interestingly, the substance does not aromatize at all, since it is a derivative of dihydrotestosterone. There are many suggestions, due to which its use is accompanied by the appearance of estrogenic adverse reactions. So what can be encountered in practice?

 Gynecomastia is a frequent athlete companion. Some suggest that Anadrol is characterized by progestogen activity. Regarding the manifestation of adverse reactions, progestins and estrogens are very similar. So at first glance the prevailing opinion may seem quite plausible.

 However, there are medical studies that clarify this issue. During them, it was revealed that no significant progestogen events were found.

 But it is worth considering the fact that Anapolon is a powerful androgen. Therefore, oily skin, increased hair growth, both on the face and on the whole body – these are all completely normal manifestations while taking this steroid.

 In addition, when using this drug, such a side effect as hepatoxic effect can show itself. The thing is that when passing through the liver tissue, Oxymetholone does not undergo splitting. It follows from this that its main component negatively affects the liver. However, it is always worth remembering rationality. Therefore, if you choose the right dosage, the toxic effect on the liver will be minimized.

Anadrol dosage

 But the most common side effect is an increase in blood pressure. The volume of fluid increases, therefore, blood pressure rises.

 Also, against the background of the use of Anapolon, migraine may occur, cholesterol levels may increase. But the rarest companion is diarrhea. For the most part, these are intestinal disorders that occur when the recommended dosage is abused.

How on the course not to face “face to face” with the side effects of Anapolon

Since the use of this steroid can be accompanied by a number of negative aspects, a significant majority are concerned with one question: “How canyou not face the side effects of Anapolon on the course?”

 So, in order to avoid all these negative phenomena, the first thing that athletes should do is include antiestrogens in their diet. For example, it can be Nolvadex or Clomid.

 In addition, you need to systematically examine the liver in order to exclude a negative effect on this organ. And since many athletes have a deficiency of iron in the blood, a biochemical blood test should be done without fail.

 To eliminate severe acne, you must include Isotretinoin (Roaccutane). And to suppress progestagenic activity, the use of a steroid steroid is necessary. To solve the problem with high blood pressure, antihypertensive drugs should be used (however, you must first consult a specialist).

Read also: 8 things to avoid during back muscle training

 But to eliminate such side effects as intestinal disorders, Smecta or Loperamide will come to the rescue.

PCT after application of Anadrol – with what “arsenal” to arm

 PCT should be started after five to seven days after the end of taking this steroid. Its duration is due not only to the long duration of the anabolic course, but also to the dosage used. To restore the natural production of testosterone, PCT after applying Anadrol should include Clomiphene Citrate (Clomid) for a duration of up to two weeks. During the first week, one tablet should be taken in the morning and evening. And during the second week, only one tablet in the morning.

 What other arsenal is worth arming? After Clomid, you should connect the Tribulus. Duration of admission is 4 weeks. Take three capsules daily.

 It is also necessary to say that at the end of the course of oxymetholone, tamoxifen is best excluded. The thing is that this drug is prone to stimulate the release of prolactin, which in turn can provoke an even greater hormonal imbalance.

 You will also need to normalize your cholesterol level. To achieve this goal, you need to correctly plan your diet and make the main emphasis on fish of fatty varieties. In addition, it will not be superfluous to additionally include a vitamin complex in the diet, in particular omega-3-acids.

 Do not forget that post-cycle therapy is a mandatory step after stopping Anadrol. After all, the further quality of life will depend on this.


The above drug is actually a powerful anabolic steroid. No wonder many call it “great and mighty.” However, it’s worthwhile to be reasonable in everything. Recommended dosages should not be neglected so as not to harm your health. He has not so many “side effects”. Well, when they occur, there are special drugs that can do this perfectly.

 Do not neglect post-cycle therapy as well – this is a mandatory step. Well and most importantly – Anadrol has proven itself among athletes, so there is no doubt in its effectiveness.

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